CLINICAL LAB BILLING

Clinical Lab Billing Services

Clinical labs submit high volumes of low-dollar claims, so medical-necessity checks and payer frequency limits make a big difference to collections.

No upfront feesHIPAA-compliantSpecialty-trained coders
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Upfront or setup fees

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Revenue cycle steps managed end to end

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Specialties and lab types we bill for

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Of your data and systems stay yours

OVERVIEW

Clinical Lab billing done right

Clinical laboratories send high volumes of low-dollar claims, so small error rates turn into large revenue losses. A missing ordering provider NPI, a CLIA number that does not match the test complexity, or a panel billed as separate components can each stop payment.

Medicare’s lab national coverage determinations (NCDs), frequency limits on tests such as lipid panels, HbA1c and vitamin D, and Advance Beneficiary Notice (ABN) rules mean coverage has to be checked at the test level, not just the claim level.

We set up lab billing to handle volume: requisition data captured accurately, tests coded and panels built correctly, frequency and NCD checks run before submission, and denials worked in batches by root cause.

Also see our medical coding, denial management, eligibility verification and revenue cycle management services.

CODING

Common clinical lab CPT & HCPCS codes we bill

Lab billing is about accuracy at volume. These codes make up a large share of most clinical lab claims.

CodeDescriptionWhat we watch for
80053Comprehensive metabolic panelAll 14 component tests must be performed to bill the panel; otherwise bill components.
80048Basic metabolic panel (calcium, total)Do not bill with 80053 for the same date; the BMP is included in the CMP.
80061Lipid panelMedicare frequency limits apply for screening; diagnosis decides coverage.
85025Complete blood count with automated differentialDo not also bill 85027 for the same specimen.
83036Hemoglobin A1cMedicare limits frequency for monitoring based on the diabetes NCD.
84443Thyroid stimulating hormone (TSH)Covered diagnoses are defined in the thyroid testing NCD.
82306Vitamin D, 25-hydroxyA frequent medical necessity denial; covered diagnoses are limited.
81001Urinalysis, automated, with microscopyChoose 81003 when no microscopy is performed.
87086Urine culture, bacterial, quantitative colony countIdentification and susceptibility codes are billed separately when performed.
36415Collection of venous blood by venipunctureBilled once per patient encounter regardless of the number of tubes.

Code descriptions are summarized. CPT® is a registered trademark of the American Medical Association. Coverage and payment rules vary by payer and change every year; we code to the current code set and your payers’ policies.

Modifiers that matter in clinical lab billing

QW

CLIA-waived testRequired by Medicare on waived tests performed under a certificate of waiver.

90

Reference (outside) laboratoryWhen the billing lab sends a test to another lab for performance.

91

Repeat clinical diagnostic lab testFor the same test repeated on the same day to get a new result, not to confirm a result.

GA

ABN on fileShows a valid Advance Beneficiary Notice was signed for a test that may be denied.

GZ

Expected denial, no ABNReports that a denial is expected and no ABN was obtained.

DENIALS

Why clinical lab claims get denied

The denial reasons we see most often in clinical lab billing, with the claim adjustment reason code (CARC) payers usually attach, and what we do so they don't happen again.

CO-50

Test not covered for the diagnosis

Medicare’s lab NCDs and payer policies list the diagnoses that support each test.

How we prevent it: We run NCD and LCD checks at the test level and track ABNs for tests that may not be covered.

CO-151

Frequency limit exceeded

Screening and monitoring tests such as lipid panels and HbA1c have payer-defined intervals.

How we prevent it: Our edits look back at prior dates of service before a repeat test is billed.

CO-B7

Lab not certified for the test

The CLIA certificate on file does not cover the complexity of the billed test.

How we prevent it: We map every test to its CLIA complexity and keep certificate data current with each payer.

CO-16

Missing ordering provider or requisition data

Claims without a valid ordering or referring NPI are rejected.

How we prevent it: Requisition data is validated at intake, and missing information is requested before the claim is built.

CO-18

Duplicate claim or service

Split specimens and repeat draws can look like duplicates to payers.

How we prevent it: We apply modifier 91 or 59 only when appropriate and hold true duplicates before submission.

HOW WE WORK

How we run your clinical lab revenue cycle

From the first eligibility check to the final patient payment, one dedicated team handles every step and reports back to you.

01

Eligibility and authorization

We verify coverage, benefits, copays and deductibles before the visit. For labs, that means validating insurance and ordering provider data from every requisition.

02

Charge capture and coding

Our coders review documentation and assign CPT, HCPCS and ICD-10-CM codes to the highest supported specificity. Panels, components and reflex tests are coded from the test menu and results.

03

Claim scrubbing and submission

Every claim is checked against NCCI edits, payer policies and modifier rules before it goes out electronically, so it is paid on the first pass.

04

Payment posting and reconciliation

We post ERAs and EOBs, compare payments to your contracted rates and flag underpayments for appeal.

05

Denial management and A/R follow-up

Every denial is worked: corrected, appealed or escalated, with root causes fed back to the front end. Denials are grouped by root cause so whole batches can be fixed and resubmitted.

06

Reporting and patient billing

You get clear monthly reports on collections, denials and A/R aging, and patients get easy-to-read statements and answers to billing questions.

COMPLIANCE

Clinical Lab payer rules we track for you

Rules that change how clinical lab claims must be coded, documented and submitted.

CLIA certification: the certificate type must support the complexity of every test billed.

National coverage determinations: Medicare has NCDs for common tests, including lipids, HbA1c, thyroid and urine cultures.

Date of service rules: specimen collection dates and the Medicare 14-day rule for hospital patients affect who can bill.

Clinical Laboratory Fee Schedule: Medicare pays most tests from the CLFS, and rates change with PAMA updates.

FAQ

Clinical Lab billing questions

Can you handle our claim volume?
Yes. Lab billing is built around volume, with automated edits, batch denial work and reporting by payer, test and ordering provider.
Do you handle patient billing for labs?
Yes. We send clear statements, answer patient calls and set up payment options, which matters for labs with high deductible patients.
What about tests that may not be covered?
We track ABNs and apply GA or GZ modifiers so you can bill the patient correctly when Medicare denies a test.
How much do your clinical lab billing services cost?
We charge a percentage of what we actually collect for you, with no upfront or setup fees. Your rate depends on claim volume and the services you need, so we quote it after a free review of your current billing.
Do we have to change our EHR or practice management system?
No. We work inside the systems you already use, and your data stays yours. We set up secure access, learn your workflows and start working claims without disrupting your front desk.

Related specialties

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